2009 © Institute for Molecular Medicine Finland FIMM
Medical Systems Biology
Besides the DNA sequence variation, it is important to understand how genes function and how RNAs, proteins, metabolites and other cellular components act together in health and disease. This area of systematic analysis and modeling of cellular functions is called systems biology. The FIMM focus is on medical systems, i.e. using systems biology to understand the pathogenesis of diseases. The major strength of the FIMM medical systems biology research is currently in cancer. The second major topic towards the future revolves around obesity and diabetes.
In cancer research, FIMM has access to globally unique capabilities for molecular profiling, functional cell analysis, bioinformatics, and mathematical modeling, and there is a possibility to develop novel insights on cancer systems biology. Olli Kallioniemi also directs the Centre of Excellence in Translational Genome-Scale Biology, which is a joint effort between VTT and Universities of Turku and Helsinki (www.tgsb.fi). For research on diabetes and obesity, there are globally competitive metabolomic profiling capabilities at VTT Espoo that are available for academic collaborations between FIMM and VTT at Espoo.
Scientific Highlights
- The 1000 Genomes Project Releases Data from Pilot Studies (22.07.2010)
- Growth Curve Analyses of Finnish Population Cohorts Shed Light on the Complex Genetic Regulation of Growth in Height (16.04.2010)
- The new Finnish Gene Atlas places Finns on the world’s genetic map (17.03.2010)
- GeneSapiens - a catalogue of expression of all human genes (23.06.2009)
- Population cohort study finds six genetic variants associated with 'bad' cholesterol (in Finnish) (27.04.2009)
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News
- Professor Juni Palmgren selected FiDiPro at FIMM (22.06.2010)
- The Nordic EMBL Partnership for Molecular Medicine officially inaugurates the Institute for Molecular Medicine Finland in Helsinki (17.03.2010)
- FIMM Annual Report 2009 (16.03.2010)
- Condolences for Leena Peltonen-Palotie (12.03.2010)
- Obituary: Professor Leena Peltonen-Palotie, Academician of Science (11.03.2010)
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