2012 © Institute for Molecular Medicine Finland FIMM
Illumina SNP and CNV Genotyping Technology
FIMM Technology Centre offers single nucleotide polymorphism (SNP) and copy number variation (CNV) genotyping with all available Illumina BeadChip and BeadArray formats for whole-genome, targeted and custom SNP and CNV sets, as well as for cytogenetic analysis needs. The supported systems include both GoldenGate and Infinium methodologies. Standard focused content chips are available for human and several other organisms (e.g. canine and porcine chips) as well as specific needs, including linkage and cancer specific panels. Custom arrays can be designed for several additional species with published sequence information available. Custom SNP sets range from 96 or 384 to 1536 SNPs per array with GoldenGate up to ~200 000 selected SNPs per array with Infinium methodology and iSelect chips.
An example of lab-workflow (Infinium), based on 200 ng of genomic DNA on Human660W-QUADchip
In addition, several data preparation and quality control steps before and after lab process are included in the standard process. All our sample and genotype data are stored in database.