Infrastructures and Services

Top-notch Infrastructure

The aim of FIMM technology platforms is to operate world-class infrastructure to enable outstanding science and early introduction of the state-of-the-art technologies in translational research and clinical operations. FIMM Technology Centre and Biobank are constantly upgrading our infrastructure to remain the state-of-the-art by further investments in the equipment (Biocenter Finland and ESFRI, the European Strategy Forum on Research Infrastructures), developing and implementing novel methods in collaboration with research groups, as well as by providing professional research services to researchers locally, nationally and internationally.

During 2014, FIMM´s research infrastructure was upgraded with a new high-throughput system for high content flow cytometric analysis. The new iQue Screener HD equipment system provided by IntelliCyt is compatible with 1,536 well plates. The system uses a patented sampling method where assay components, typically suspension cells, are transferred in suspension to the detector in a continuous, air gap delimited stream. FIMM’s equipment is the first of its kind in Europe. The new system is especially useful for FIMM’s translational research projects aiming to develop truly personalised approaches to patient treatment. The new system enables the personalised medicine team to set up new and more complex flow cytometric assays that will give more detailed information about the effect of the drugs on cells.

FIMM’s new iQue Screener equipment system is the first of its kind in Europe.

Technology Centre’s Sequencing Unit increased its’ service capacity by purchasing a new Illumina HiSeq 2500 sequencing machine to meet the latest specifications of the rapidly developing field. The new machine can produce up to 1 Tbp of sequence in six days, thus speeding up the project turnaround time and enabling true genome-scale sequencing. The novel technology and chemistry enabled us to produce more high quality sequence data with less money, which was visible to the users already during 2014 by reduced prices of the services. FIMM Next Generation Sequencing (NGS) fleet now runs with 2 HiSeq2500, 1 HiSeq1500 reserved for clinical sequencing, and a MiSeq benchtop sequencer.

Infrastructure Milestones 2014

ESFRIs and National Roadmap

FIMM is involved in five research infrastructures included in the national roadmap that was published in March 2014. In addition to Biocenter Finland that continues its functions, EATRIS, EU-OPENSCREEN, BBMRI and EURO-BIOIMAGING were included in the roadmap. Both EATRIS and BBMRI have received the status of an ERIC (European Research Infrastructure Consortium). This specific legal form is designed to facilitate the joint establishment and operation of research infrastructures of European interest. Professor Olli Kallioniemi is the national coordinator of EATRIS as well as chairs the EATRIS Biomarkers Product Group - one of the five technology areas in EATRIS. Dr. Krister Wennerberg acts as a national coordinator of EU-OPENSCREEN. The day-to-day work is carried out by Project Director Andreas Scherer and Research Coordinator Heidi Virtanen.

Academy of Finland Infrastructure Funding

Finnish Research Infrastructure (FIRI) Committee of the Academy of Finland monitors and develops Finnish and international research infrastructure activities and selects the infrastructure projects to be funded in Finland. In the FIRI 2014 call, the EATRIS and the EU-OPENSCREEN infrastructures received funding. EATRIS funding was mainly allocated for national coordination of this ESFRI project.

Ongoing EU Infrastructure Projects

Project

Years

Link

Project Description

BioMedBridges

2012-2015

www.biomedbridges.eu

 

Building Data Bridges between Biological and Medical Infrastructures in Europe

 

BBMRI-LPC

2013-2017

www.bbmri-lpc.org

 

European Biobanking and Biomolecular Research Infrastructure - Large Prospective Cohorts

 

 

Infrastructures and Services