FIMM "Think Different" Seminar Series by Caroline Dive | Biomedicum 1, Lecture Hall 2


Monday, February 2, 2015 - 10:15 to 11:15


The "Think Different" seminar series is organized by doctoral students at FIMM. For the series, researchers working on exciting new ideas are invited once a month to give a talk and hopefully encourage the audience to think different.

On Feb 2nd Prof. Caroline Dive from CRUK Manchester will give us an exciting talk on: 'What use are circulating tumour cells in cancer research? Biomarkers? Biology? Tumour heterogeneity?  Mouse models?'


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About the speaker:

Professor Caroline Dive, is Professor of Pharmacology at Manchester University and since 2004 Senior Group Leader at the University's Paterson Institute for Cancer Research, where she heads the Clinical and Experimental Pharmacology (CEP) Group. She has also worked with the Translational Medicine Drug Development Group at the Manchester Cancer Research Centre (MCRC) since 2005. Professor Dive has >249 papers to her name in the world's leading journals. Her laboratory's interest is in circulating biomarkers for noninvasive diagnosis, prediction of drug response, and/or monitoring of drug effects (efficacy and/or toxicity). Dr.Caroline Dive's lab has worked extensively on use of circulating tumor cells (CTCs) as diagnostic markers in the context of personalized medicine initiatives especially in lung cancers and other solid tumors.

Key publications:

Hodgkinson, C. L., Morrow, C. J., Li, Y., Metcalf, R. L., Rothwell, D. G., Trapani, F., ... & Dive, C. (2014). Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer. Nature Medicine.
Krebs, M. G., Metcalf, R. L., Carter, L., Brady, G., Blackhall, F. H., & Dive, C. (2014). Molecular analysis of circulating tumour cells [mdash] biology and biomarkers. Nature Reviews Clinical Oncology.
Hou, J. M., Krebs, M. G., Lancashire, L., Sloane, R., Backen, A., Swain, R. K., ... & Dive, C. (2012). Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer. Journal of Clinical Oncology, 30(5), 525-532.
Khoja, L., Lorigan, P., Zhou, C., Lancashire, M., Booth, J., Cummings, J., ... & Dive, C. (2012). Biomarker utility of circulating tumor cells in metastatic cutaneous melanoma. Journal of Investigative Dermatology, 133(6), 1582-1590.
Last updated: 26.01.2015 - 14:41