Dr. Gretchen Repasky received her undergraduate training at Lehigh University (USA) followed by her PhD in cell and molecular biology from New York University (USA) in 2000. She then expanded on her studies of small GTPase intracellular signaling mechanisms by joining Channing Ders group the University of North Carolina at Chapel Hill (USA) as a Merck Postdoctoral Fellow of the Life Science Research Foundation where she focused on Ras family protein-mediated oncogenesis. Subsequently, she held an assistant professor faculty position at Birmingham-Southern College in Birmingham, Alabama (USA) before relocating to Helsinki in 2010 to serve as the research training coordinator at FIMM. In this capacity, Gretchen has developed and manages the FIMM-EMBL International PhD program, as well as FIMMPOD, FIMMs professional development program for postdoctoral and senior researchers. In addition, she coordinates FIMMs Doctoral Training Committee, plans courses and symposia, advises doctoral candidates, and handles other educational initiatives. As a senior researcher, her current research interests and efforts lie within the scope of cancer chemical biology in Krister Wennerbergs group, and she previously served as a member of FIMMs team in the EU-OPENSCREEN ESFRI project working to design and construct an open access infrastructure for high throughput chemical screening in Europe.
Pemovska T., Johnson E., Kontro M., Repasky G.A., Chen J., Wells P., Cronin C.N., McTigue M., Kallioniemi O., Porkka K., Murray B.W., Wennerberg K. (2015) Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation. Nature. 519:102-105. PMID: 25686603
Frankowiack M., Kovanen R., Repasky G.A., Lim C.K., Song C., Pedersen N.L., Hammarström L. (2015) The higher frequency of IgA deficiency among Swedish twins is not explained by HLA haplotypes. Genes Immun. Epub. PMID: 25569265
van Adrichem J., Fagerholm A., Turunen L., Lehto A., Saarela J., Koskinen A., Repasky G.A., Wennerberg K., (2014) Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP. Comb Chem High Throughput Screen. Epub. PMID: 25479424