Pirkko Mattila

Pirkko Mattila, Ph.D., Docent, is a Senior Researcher at the Sequencing Unit. The unit provides next generation sequencing (NGS ) as well as capillary sequencing services for national and international research groups. Dr. Mattila has strong background in molecular biology and transcriptomics. Her work includes project planning and management, data handling, analysis and quality assessment of RNAseq data. She is actively developing methods for RNAseq and miRseq applications and participates in educational activities with special focus of transcriptomics. Her latest interest lies in the technologies enabling capture and processing of single cells for sequencing and other downstream applications. Currently, Pirkko Mattila is a joint researcher at FIMM and in Finnish Red Cross Blood Service (FRCBS). In FRCBS (one partner of Get It Done -program), Pirkko is establishing and managing research projects led by Salwe Ltd, a Tekes funded Strategic Center for Science, Technology and Innovation in Health.

Selected publications

Joenväärä S, Mattila P, Renkonen J, Mäkitie A,Toppila-Salmi S, Lehtonen M, Salmi P, Lehti S, Mäkinen J, Sormunen R, Paavonen T, Renkonen R. Caveolar transport through nasal epithelium of birch pollen allergen Bet v 1 in allergic patients. J Allergy Clin Immunol. 2009 Jul;124(1):135-142.

Mattila P, Renkonen J, Toppila-Salmi S, Parviainen V, Joenväärä S, Alff-Tuomala S, Nicorici D, Renkonen R. Time-series nasal epithelial transcriptomics during natural pollen exposure in healthy subjects and allergic patients. Allergy 2010 Feb; 65(2):175-83.

Renkonen J, Mattila P, Parviainen V, Joenväärä S, Toppila-Salmi S, Renkonen R. A network analysis of the single nucleotide polymorphisms in acute allergic diseases.  Allergy. 2010 Jan;65(1):40-7. Epub 2009 Oct 1.

Koskela HL, Eldfors S, Ellonen P, van Adrichem AJ, Kuusanmäki H, Andersson EI, Lagström S, Clemente MJ, Olson T, Jalkanen SE,Majumder MM, Almusa H, Edgren H, Lepistö M, Mattila P, Guinta K, Koistinen P, Kuittinen T, Penttinen K, Parsons A, Knowles J, Saarela J, Wennerberg K, Kallioniemi O, Porkka K, Loughran TP Jr, Heckman CA, Maciejewski JP, Mustjoki S. Somatic STAT3 mutations in large granular lymphocytic leukemia.  N Engl J Med. 2012 May 17;366(20):1905-13. doi: 10.1056/NEJMoa1114885.

Pemovska T, Kontro M, Yadav B, Edgren H, Eldfors S, Szwajda A, Almusa H, Bespalov MM,  Ellonen P, Elonen E, Gjertsen BT, Karjalainen R, Kulesskiy E, Lagström S, Lehto A, Lepistö M, Lundán T, Majumder MM, Marti JM, Mattila P, Murumägi A, Mustjoki S, Palva A, Parsons A, Pirttinen T, Rämet ME, Suvela M, Turunen L, Västrik I, Wolf M, Knowles J, Aittokallio T, Heckman CA, Porkka K, Kallioniemi O, Wennerberg K. Individualized systems medicine strategy to tailor Dec;3(12):1416-29. doi: 10.1158/2159-8290.CD-13-0350. Epub 2013 Sep 20.PMID: 24056683.

Internal links

External links

Pirkko Mattila
+358 50 317 5434

Job title

Senior Researcher, Head of Unit

Areas of expertise

Transcriptomics
Molecular biology
Next Generation Sequencing (NGS)
RNAseq
miRseq

Started at FIMM

2010

Degrees

M.Sc.(Biochemistry), University of Helsinki, 1989
Ph.D. (Biochemistry), University of Helsinki, 1993
Title of Docent (Biochemistry), University of Helsinki, 2011
Last updated: 12.09.2017 - 15:49