Near-simultaneous intensive care unit (ICU) admissions and all-cause mortality: a cohort study.
Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study.
Failure in the compensatory mechanism in red blood cells due to sustained smoking during pregnancy.
Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions.
Chemogenomic Analysis of the Druggable Kinome and Its Application to Repositioning and Lead Identification Studies.
Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022.
Structure of Salmonella Flagellar Hook Reveals Intermolecular Domain Interactions for the Universal Joint Function.
Correction: Phenotypic spectrum associated with a CRADD founder variant underlying frontotemporal predominant pachygyria in the Finnish population.
A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity.
The Prognostic Value of Blood and Lymphatic Vessel Markers in Tongue Cancer: A Systematic Review.
No Association Between Genetic Loci Near IRF2 and TBX1 and Acute Kidney Injury in the Critically Ill.
Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer's disease.
Prevalence and correlates of dementia and mild cognitive impairment classified with different versions of Telephone Interview for Cognitive Status-modified (TICS-m).
Eating Behaviors in Healthy Young Adult Twin Pairs Discordant for Body Mass Index.
EpiSmokEr: a robust classifier to determine smoking status from DNA methylation data.
Prognostic role of body composition parameters in gastric/gastroesophageal junction cancer patients from the EXPAND trial.
Multi-parametric single cell evaluation defines distinct drug responses in healthy hematological cells that are retained in corresponding malignant cell types.
Physical Activity and Academic Performance: Genetic and Environmental Associations.
Reply to Mengxin Lu, Yi Zhang, Yu Xiao's Letter to the Editor, re: Kimmo Kettunen, Peter J. Boström, Tarja Lamminen, et al. Personalized Drug Sensitivity Screening for Bladder Cancer Using Conditionally Reprogrammed Patient-derived Cells. Eur Urol. I
Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes.
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins.
Donor Simvastatin Treatment in Heart Transplantation: A Randomized and Blinded Clinical Trial.
Is diversity of leisure-time sport activities associated with low back and neck-shoulder region pain? A Finnish twin cohort study.
Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals.
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy combined with liver resection for concurrent peritoneal and hepatic metastases of gastrointestinal and gynecological primary tumors.
Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify Kras Mutant Lung Cancers.
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data.
Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer.
Integrated targeted metabolomic and lipidomic analysis: A novel approach to classifying early cystic precursors to invasive pancreatic cancer.
Long-Term Physical Activity May Modify Brain Structure and Function: Studies in Young Healthy Twins.
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.
Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches.
Positive STAT5 protein and locus amplification status predicts recurrence after radical prostatectomy to assist clinical precision management of prostate cancer.
Tumor expression of human chorionic gonadotropin beta mRNA and prognosis of prostate cancer treated by radical prostatectomy.
Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia.
Fibroblast as a critical stromal cell type determining prognosis in prostate cancer.
Coronary Artery Disease Risk and Lipidomic Profiles Are Similar in Hyperlipidemias With Family History and Population-Ascertained Hyperlipidemias.
CTCF variants in 39 individuals with a variable neurodevelopmental disorder broaden the mutational and clinical spectrum.
High levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) in the serum are associated with poor prognosis in HPV-negative squamous cell oropharyngeal cancer.
Physical activity associates with subarachnoid hemorrhage risk- a population-based long-term cohort study.
Intertumoral heterogeneity in patient-specific drug sensitivities in treatment-naïve glioblastoma.
Increasing Prepregnancy Obesity Is Associated with Large-for-Gestational Age Infants Among a Diverse, Contemporary Cohort (P11-018-19).
Pressurized intraperitoneal aerosol chemotherapy with low-dose cisplatin and doxorubicin (PIPAC C/D) in patients with gastric cancer and peritoneal metastasis: a phase II study.
Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen.
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
Seipin Facilitates Triglyceride Flow to Lipid Droplet and Counteracts Droplet Ripening via Endoplasmic Reticulum Contact.
Hierarchical clustering in evaluating inflammatory upper airway phenotypes; increased symptoms in adults with allergic multimorbidity.
Elevated expression of S100A8 and S100A9 correlates with resistance to the BCL-2 inhibitor venetoclax in AML.
Childlessness and union histories: evidence from Finnish population register data.
Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability.
Comparison of PI-RADS v1 and v2 for multiparametric MRI detection of prostate cancer with whole-mount histological workup as reference standard.
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland.
Validation of IMPROD biparametric MRI in men with clinically suspected prostate cancer: A prospective multi-institutional trial.
Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.
OCT-elastography-based optical biopsy for breast cancer delineation and express assessment of morphological/molecular subtypes.
Pregnancy-associated stroke -a systematic review of subsequent pregnancies and maternal health.
Variants in regulatory elements of PDE4D associate with major mental illness in the Finnish population.
Fast prostate retrieval in robot-assisted laparoscopic prostatectomy for next-generation biobanking.
In situ hybridization for high-risk HPV E6/E7 mRNA is a superior method for detecting transcriptionally active HPV in oropharyngeal cancer.
A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis.
Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer.
Machine-learned analysis of the association of next-generation sequencing based genotypes with persistent pain after breast cancer surgery.
Prediction of the 1-Year Risk of Incident Lung Cancer: Prospective Study Using Electronic Health Records from the State of Maine.
Cumulative Cancer Locations is a Novel Metric for Predicting Active Surveillance Outcomes: A Multicenter Study.
Testing the reciprocal association between smoking and depressive symptoms from adolescence to adulthood: A longitudinal twin study.
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
Variant Score Ranker-a web application for intuitive missense variant prioritization.
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
A nearly fatal primary Epstein-Barr virus infection associated with low NK-cell counts in a patient receiving azathioprine: a case report and review of literature.
In-bore biopsies of the prostate assisted by a remote-controlled manipulator at 1.5 T.
Predictive Association of Smoking with Depressive Symptoms: a Longitudinal Study of Adolescent Twins.
Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets.
Further support linking the 22q11.2 microduplication to an increased risk of bladder exstrophy and highlighting LZTR1 as a candidate gene.
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Power of computed-tomography-defined sarcopenia for prediction of morbidity after pancreaticoduodenectomy.
Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers.
Plasma Heme Scavengers Alpha-1-Microglobulin and Hemopexin as Biomarkers in High-Risk Pregnancies.
Accurate early prediction of tumour response to PDT using optical coherence angiography.
A2ML1 and otitis media: novel variants, differential expression and relevant pathways.
Association of snus experimentation in late adolescence with daily cigarette smoking in early adulthood: A longitudinal study among Finnish men.
A within-sibling pair analysis of lifestyle behaviours and BMI z-score in the multi-centre I.Family study.
Parental Education and Genetics of BMI from Infancy to Old Age: A Pooled Analysis of 29 Twin Cohorts.
Hemap: An interactive online resource for characterizing molecular phenotypes across hematologic malignancies.
Biallelic loss-of-function P4HTM gene variants cause hypotonia, hypoventilation, intellectual disability, dysautonomia, epilepsy, and eye abnormalities (HIDEA syndrome).
Bayesian meta-analysis across genome-wide association studies of diverse phenotypes.
Phenotypic spectrum associated with a CRADD founder variant underlying frontotemporal predominant pachygyria in the Finnish population.
FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis.
Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans.
The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects.
Detection of breast cancer lymph node metastases in frozen sections with a point-of-care low-cost microscope scanner.
Shift in translations: Data work with patient-generated health data in clinical practice.
Common Inflammation-Related Candidate Gene Variants and Acute Kidney Injury in 2647 Critically Ill Finnish Patients.
Computational analysis of the evolutionarily conserved Missing In Metastasis/Metastasis Suppressor 1 gene predicts novel interactions, regulatory regions and transcriptional control.
Return to work after sickness absence: a register-based comparison of two indigenous population groups.
The Apolipoprotein E4 polymorphism and outcomes from traumatic brain injury: a living systematic review and meta-analysis.
Patients with rheumatic diseases share similar patterns of healthcare resource utilization.
Impact of Nutritional Intake on Function in People with Mild-to-Moderate Multiple Sclerosis.
Low Temperature and Low UV Indexes Correlated with Peaks of Influenza Virus Activity in Northern Europe during 2010⁻2018.
Temporal and external validation of the fullPIERS model for the prediction of adverse maternal outcomes in women with pre-eclampsia.
Maternal depressive symptoms during and after pregnancy are associated with poorer sleep quantity and quality and sleep disorders in 3.5-year-old offspring.
Publisher Correction: Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
Quantitative nontumorous and tumorous human brain tissue assessment using microstructural co- and cross-polarized optical coherence tomography.
Birch pollen allergen immunotherapy reprograms nasal epithelial transcriptome and recovers microbial diversity.
Drug sensitivity testing on patient-derived sarcoma cells predicts patient response to treatment and identifies c-Sarc inhibitors as active drugs for translocation sarcomas.
Letter on "Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis".
Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
Repeated Transcranial Magnetic Stimulation-Induced Motor Evoked Potentials Correlate With the Subject-Specific Serum Metabolic Profile of Creatine.
Correction to: Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study.
Association Between Serum Lipid Profile and Obstructive Respiratory Events During REM and Non-REM Sleep.
Combining CDKN1A gene expression and genome-wide SNPs in a twin cohort to gain insight into the heritability of individual radiosensitivity.
Heredity of interocular similarities in components of refraction: a population-based twin study among 66- to 79-year-old female twins.
Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity - A Study on Rare Bmi-Discordant Monozygotic Twin Pairs.
TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration.
Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland.
Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Metastases in Solid Organ Graft Recipients: First Experience.
Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances.
Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL.
Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study.
Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting.
Chronic diseases and objectively monitored physical activity profile among aged individuals - a cross-sectional twin cohort study.
Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
Is Left Ventricular Global Longitudinal Strain by Two-Dimensional Speckle Tracking Echocardiography in Sepsis Cardiomyopathy Ready for Prime Time Use in the ICU?
Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci.
Last updated: 03.01.2019 - 09:58