Sample storage facility which provides low-cost, secure and controlled storage of samples in liquid nitrogen vapor phase. At the moment the system has the capacity to store over 600 000 samples. This LN2 based sample storage is available to all research groups on the campus and elsewhere for storing small and medium sized sample collections. In addition to LN2 samples can be stored in -20C, -80C or room temperature when appropriate. For most widely used sample collections MIBI has an automated storage system NitroStore. The capacity of NitroStore is 200 000 samples, 100 000 in -20C, and -80C each. NitroStore significantly increases productivity by speeding up cherry picking of samples.
Automated sample processing
MIBI offers automated DNA extraction service from whole blood, buffy coats, cell and tissue samples, saliva and buccal swabs, as well as automated DNA aliquoting including normalization and quality control. Similarly, liquid handling robotics allows automated serum and plasma aliquoting if needed.
Biobank informatics provides a range of critical services to facilitate biobank activities, from standardized annotation ontologies, to methods for handling large, multidimensional datasets. MIBI has developed an in-house database/LIMS system for biobanking called SamWise. Additionally, MIBI provides database services for hosting, management and curation of clinical and research data associated with biobanks as well as data collection and federation services.
Cell technologies laboratory at MIBI provides help for collecting, isolating and storing various cell samples as well as establishing cell lines for research purposes and for clinical projects. The novel iPSC (induced pluripotent stem cell) technique has enormous research potential for utilization of cells stored in the biobanks, since iPSCs can be differentiated into various cell types. In collaboration with the Biomedicum Stem cell Centre, production of iPSC can be provided from blood mononuclear cells, immortalized B-lymphocyte lines and fibroblasts.