Extracellular Vesicles Core
EV Core is the world’s first technology platform dedicated to Extracellular Vesicle isolation and analytics.
The EV Core is divided to two units, where EV Core FIMM focuses on EVs from liquid biopsy samples, including isolation and analysis of EV-RNA as well as electron microscopy samples. EV Core Viikki is dedicated to the characterization of EVs using NTA and Apogee micro flow cytometer, and functional assays. Both units work together to develop SOPs for sample handling, EV isolations and downstream applications and to test new methods. In conclusion, the EV Core is a new and globally unique technology core providing EV know-how and the necessary tools for characterization and downstream analyses of EVs.
What are EVs?
Extracellular vesicles (EVs) such as exosomes and microvesicles are small vesicles secreted by cells to blood and other biofluids. Since EVs have been shown to contain a rich biomolecule content and play a key role in cell-cell communication, EVs are a significant sample source for diagnostic and therapeutic applications. EV research field is still young, but has already witnessed an exponential rise in discoveries and applications in areas from basic science to translational medicine. However, the unmet need for specific analysis equipment, standardization and knowhow in the study set-up (data normalization, controls, and standards), purification and basic characterization of EVs hinders the progress.