Location

Tuesday, October 10, 2017 - 08:30 to Wednesday, October 11, 2017 - 16:00

 

EU-LIFE JOINT COURSE
6th Building Bridges Symposium: Epigenetics in Clinical and Translational Research
October 10-11, 2017
Biomedicum Helsinki, Finland

 

The Building Bridges symposia series is arranged to bridge clinical and basic/translational research and provide examples of how teams of investigators are working together towards a better understanding of the pathophysiology of disease and improved options for patient treatment and care. 

The 6th Building Bridges symposium will highlight how epigenetics research can be leveraged to improve our understanding of health and disease.  We set the stage by learning about the basics:  What is epigenetics?  How can studying epigenetics enable precision medicine?  Then, with research-focused talks from clinical and translational researchers, we explore detailed examples of discovery, development, and application in the areas of 1) epigenomics, 2) cell differentiation in disease, and 3) epigenetic modifiers as drug targets.  We close the symposium by engaging the public in the future societal applications of epigenetics research.

Join us for the latest insights into epigenetics and epigenomics research and a special outreach session to the general public!

Please visit the Symposium main page for more information! 

 

Participants

The course is targeted both as an introduction to epigenetics as well as a demonstration of advancements in epigenetics research.  As such, the events are open to the entire scientific community.  Doctoral candidates wishing to learn about epigenetics, especially in relation to human health and disease, are encouraged to attend.

 

Organizers

Institute for Molecular Medicine Finland (FIMM), Centre for Genomic Regulation (CRG, Barcelona), EU-LIFE, University of Helsinki Doctoral Programmes in Biomedicine (DPBM), Clinical Research (KLTO), and Population Health (DocPop).

Registration

Registration is open June 1 through September 15, 2017.

Please register with this form. More information here
 

Program

08.30 MORNING COFFEE
08.50 WELCOMING WORDS FROM THE ORGANIZERS

SESSION I: SETTING THE STAGE
Chair: Gretchen Repasky
09.00 Luciano Di Croce (Centre for Genomic Regulation, Spain): The basics of epigenetics

SESSION II: EARLY LIFE EXPOSURE AND EPIGENETICS
Chair: Nina Kaminen-Ahola
09.40 Team talk: Biomarkers for fetal alcohol spectrum disorder
Nina Kaminen-Ahola (University of Helsinki, Finland) and Hanna Kahila (Helsinki University Central Hospital, Finland)
10.25 STRETCH BREAK
10.35 Robert Lyle (Oslo University Hospital, Norway):
Prenatal exposure to paracetamol and its association with ADHD
11.15 Jari Lahti (Helsinki Collegium for Advanced Studies, University of Helsinki):
Pre- and perinatal factors influence epigenetic clock in cord blood
11.45 Epigenetics in health and disease speed talks (doctoral candidates/postdocs)
12.00 LUNCH                                                                      
“Lunch & Learn” for select doctoral candidates 
Doctoral candidates are welcome to join speakers to discuss career management and development over lunch.

SESSION III: EPIGENOMICS
Chair: Miina Ollikainen
13.15 Jordana Bell (Kings College London, UK)
Epigenomic studies in twins
14.00 Charlotte Ling (Lund University, Sweden):
Epigenetic mechanisms in type 2 diabetes and metabolic diseases
14.45 COFFEE BREAK
15.15 Riikka Lund (Finnish Functional Genomics Centre, Finland):
DNA methylation changes associated with genomic instability and diseases 
15.45 Caroline Relton (University of Bristol, UK): TBA
16.30 Epigenomics speed talk (doctoral candidates/postdocs)
   
October 11, 2017
08.30 MORNING COFFEE
08.50 Perspectives on the first day from the organizers

SESSION IV: CELL DIFFERENTIATION AND EPIGENETICS IN DISEASE AND THERAPY
Chair: Luciano Di Croce
9.00 Team talk: Epigenetics in Cancer
Luciano Di Croce (Center for Genomic Regulation, Spain) and Saverio Minucci (European Institute of Oncology, Italy)
9.45 Jean-Christophe Marine (VIB Leuven, Belgium):
From new insights into melanoma biology to improved targeted therapies 
10.25 STRETCH BREAK
10.35 Eric So (King's College London, UK):
Histone methylome as a therapeutic target in AML 
11.15 Keijo Viiri (Center for Child Health Research, University of Tampere, Finland):
The epigenetic reign of intestinal differentiation and homeostasis and aberrancies in celiac disease 
11.45 Epigenetics in disease and therapy speed talks (doctoral candidates/postdocs)
12.00 LUNCH
For limited number of doctoral students:  
“Lunch & Learn” for select doctoral candidates
Doctoral candidates are welcome to join speakers to discuss specific scientific topics and hurdles in translational research over lunch.

SESSION V: EPIGENETICS AND SOCIETY 
Chair: Gretchen Repasky and The Science Basement
13.15 Romain Barres (Environmental Epigenetics, University of Copenhagen, Denmark):
Epigenetic inheritance or the influence of ancestral lifestyle on the next generation – implication for health and evolution 
14.00 Team talk: Clinician and researcher discuss risk for obesity and how lifestyle can modify gene action in obesity
Miina Ollikainen (Institute for Molecular Medicine Finland University of Helsinki, Finland) and Kirsi Pietiläinen (University of Helsinki, Finland)
14.45 Science Café
Round table discussions with experts 
(1-2 experts/table, both English and Finnish speaking tables) 

Confirmed table experts:

  • Romain Barres (University of Copenhagen, Denmark)
  • Luciano Di Croce (Center for Genomic Regulation, Spain)
  • Chiara Facciotto (University of Helsinki)
  • Robert Lyle (Oslo University Hospital, Norway)
  • Nina Kaminen-Ahola (University of Helsinki, Finland)
  • Heidi Marjonen (University of Helsinki, Finland)
  • Miina Ollikainen (Institute for Molecular Medicine Finland, University of Helsinki)
  • Kirsi Pietiläinen (University of Helsinki, Finland)
15.50 CLOSING WORDS

 

Last updated: 06.06.2017 - 11:57